Products

Enzyme-linked Immunoabsorbent Assay

Western Blot (Recombinant protein)

Antibody Production

Protein Array

Entrez GeneID

GeneBank Accession#

Protein Accession#

Gene Name

TFAP2B

Gene Alias

AP-2B, AP2-B, MGC21381

Gene Description

transcription factor AP-2 beta (activating enhancer binding protein 2 beta)

Omim ID

Gene Ontology

Gene Summary

This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives. [provided by RefSeq

Other Designations

OTTHUMP00000039925|activating enhancer binding protein 2 beta|transcription factor AP-2 beta