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Last updated: 2016/12/4

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TFAM rabbit monoclonal antibody

  • Catalog # : H00007019-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human TFAM peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human TFAM is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human TFAM peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 7019
  • GeneBank Accession#:
  • TFAM
  • Gene Name:
  • TFAM
  • Gene Alias:
  • MtTF1,TCF6,TCF6L1,TCF6L2,TCF6L3,mtTFA
  • Gene Description:
  • transcription factor A, mitochondrial
  • Gene Summary:
  • This gene encodes a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this gene product is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns-Sayre syndrome was produced when expression of this gene was eliminated by targeted disruption in heart and muscle cells. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000019633,Transcription factor 6-like 2 (mitochondrial transcription factor),mitochondrial transcription factor A
  • Gene Pathway
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