TEAD3 monoclonal antibody (M01), clone 1C4
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant TEAD3.
Immunogen
TEAD3 (NP_003205, 215 a.a. ~ 302 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
WQDRTIASSRLRLLEYSAFMEVQRDPDTYSKHLFVHIGQTNPAFSDPPLEAVDVRQIYDKFPEKKGGLKELYEKGPPNAFFLVKFWAD
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (100); Rat (100)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged TEAD3 is 0.03 ng/ml as a capture antibody.ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to TEAD3 on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — TEAD3
Entrez GeneID
7005GeneBank Accession#
NM_003214Protein Accession#
NP_003205Gene Name
TEAD3
Gene Alias
DTEF-1, ETFR-1, TEAD5, TEF-5, TEF5
Gene Description
TEA domain family member 3
Omim ID
603170Gene Ontology
HyperlinkGene Summary
This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. It is predominantly expressed in the placenta and is involved in the transactivation of the chorionic somatomammotropin-B gene enhancer. Translation of this protein is initiated at a non-AUG (AUA) start codon. [provided by RefSeq
Other Designations
OTTHUMP00000039597|TEA domain family member 5|Transcriptional enhancer factor TEF-5 (DTEF-1)|transcriptional enhancer factor 5
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Interactome
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Publication Reference
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Systems-based identification of the Hippo pathway for promoting fibrotic mesenchymal differentiation in systemic sclerosis.
Feiyang Ma, Pei-Suen Tsou, Mehrnaz Gharaee-Kermani, Olesya Plazyo, Xianying Xing, Joseph Kirma, Rachael Wasikowski, Grace A Hile, Paul W Harms, Yanyun Jiang, Enze Xing, Mio Nakamura, Danielle Ochocki, William D Brodie, Shiv Pillai, Emanual Maverakis, Matteo Pellegrini, Robert L Modlin, John Varga, Lam C Tsoi, Robert Lafyatis, J Michelle Kahlenberg, Allison C Billi, Dinesh Khanna, Johann E Gudjonsson.
Nature Communications 2024 Jan; 15(1):210.
Application:IF, Human, Skin.
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Systems-based identification of the Hippo pathway for promoting fibrotic mesenchymal differentiation in systemic sclerosis.
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