TCN2 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human TCN2 full-length ORF ( AAH01176, 20 a.a. - 427 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MCEIPEMDSHLVEKLGQHLLPWMDRLSLEHLNPSIYVGLRLSSLQAGTKEDLYLHSLKLGYQQCLLGSAFSEDDGDCQGKPSMGQLALYLLALRANCEFVRGHKGDRLVSQLKWFLEDEKRAIGHDHKGHPHTSYYQYGLGILALCLHQKRVHDSVVDKLLYAVEPFHQGHHSVDTAAMAGLAFTCLKRSNFNPGRRQRITMAIRTVQEEILKAQTPEGHFGNVYSTPLALQFLMTSPMRGAELGTACLKARVALLASLQDGAFQNALMISQLLPVLNHKTYIDLIFPDCLAPRVMLEPAAETIPQTQEIISVTLQVLSLLPPYRQSISVLAGSTVEDVLKKAHELGGFTYETQASLSGPYLTSVMGKAAGEREFWQLLRDPNTPLLQGIADYRPKDGETIELRLVSW
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
70.62
Interspecies Antigen Sequence
Mouse (73)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — TCN2
Entrez GeneID
6948GeneBank Accession#
BC001176Protein Accession#
AAH01176Gene Name
TCN2
Gene Alias
D22S676, D22S750, TC2
Gene Description
transcobalamin II; macrocytic anemia
Omim ID
275350Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This plasma protein binds cobalamin and mediates the transport of cobalamin into cells. This protein and other mammalian cobalamin-binding proteins, such as transcobalamin I and gastric intrisic factor, may have evolved by duplication of a common ancestral gene. [provided by RefSeq
Other Designations
transcobalamin II
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Interactome
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Disease
- Abortion
- Adenocarcinoma
- Alcoholism
- Anemia
- Aortic Aneurysm
- Atherosclerosis
- Autistic Disorder
- Avitaminosis
- Brain Ischemia
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