TCN2 monoclonal antibody (M01), clone 2F4
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant TCN2.
Immunogen
TCN2 (AAH11239, 1 a.a. ~ 400 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MRHLGAFLFLLGVLGALTEMCEIPEMDSHLVEKSGQHLLPWMDRLSLEHLNPSIYVGLRLSSLQAGTKEDLYLHSLKLGYQQCLLGSAFSEDDGDCQGKPSMGQLALYLLALRANWHDHKGHPHTSYYQYGLGILALCLHQKRVHDSVVDKLLYAVEPFHQGHHSVDTAAMAGLAFTCLKRSNFNPGRRQRITMAIRTVREEILKAQTPEGHFGNVYSTPLALQFLMTSPMRGAELGTACLKARVALLASLQDGAFQNALMISQLLPVLNHKTYIDLIFPDCLAPRVMLEPAAETIPQTQEIISVTLQVLSLLPPYRQSISVLAGSTVEDVLKKAHELGGFTYETQASLSGPYLTSVMGKAAGEREFWQLLRDPNTPLLQGIADYRPKDGETIELRLVSW
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (67)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (69.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of TCN2 expression in transfected 293T cell line by TCN2 monoclonal antibody (M01), clone 2F4.
Lane 1: TCN2 transfected lysate (Predicted MW: 47.5 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged TCN2 is 1 ng/ml as a capture antibody.ELISA
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Gene Info — TCN2
Entrez GeneID
6948GeneBank Accession#
BC011239Protein Accession#
AAH11239Gene Name
TCN2
Gene Alias
D22S676, D22S750, TC2
Gene Description
transcobalamin II; macrocytic anemia
Omim ID
275350Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This plasma protein binds cobalamin and mediates the transport of cobalamin into cells. This protein and other mammalian cobalamin-binding proteins, such as transcobalamin I and gastric intrisic factor, may have evolved by duplication of a common ancestral gene. [provided by RefSeq
Other Designations
transcobalamin II
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Interactome
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Disease
- Abortion
- Adenocarcinoma
- Alcoholism
- Anemia
- Aortic Aneurysm
- Atherosclerosis
- Autistic Disorder
- Avitaminosis
- Brain Ischemia
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