TCN2 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human TCN2 peptide using ARM Technology.
Immunogen
A synthetic peptide of human TCN2 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human TCN2 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — TCN2
Entrez GeneID
6948GeneBank Accession#
TCN2Gene Name
TCN2
Gene Alias
D22S676, D22S750, TC2
Gene Description
transcobalamin II; macrocytic anemia
Omim ID
275350Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This plasma protein binds cobalamin and mediates the transport of cobalamin into cells. This protein and other mammalian cobalamin-binding proteins, such as transcobalamin I and gastric intrisic factor, may have evolved by duplication of a common ancestral gene. [provided by RefSeq
Other Designations
transcobalamin II
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Interactome
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Disease
- Abortion
- Adenocarcinoma
- Alcoholism
- Anemia
- Aortic Aneurysm
- Atherosclerosis
- Autistic Disorder
- Avitaminosis
- Brain Ischemia
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