HNF1A monoclonal antibody (M01), clone 6G4
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant HNF1A.
Immunogen
HNF1A (P20823, 532 a.a. ~ 631 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
ALASLTPTKQVFTSDTEASSESGLHTPASQATTLHVPSQDPAGIQHLQPAHRLSASPTVSSSSLVLYQSSDSSNGQSHLLPSNHSVIETFISTQMASSSQ
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (89); Rat (88)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
HNF1A monoclonal antibody (M01), clone 6G4. Western Blot analysis of HNF1A expression in human colon.Western Blot (Cell lysate)
HNF1A monoclonal antibody (M01), clone 6G4. Western Blot analysis of HNF1A expression in U-2 OS.Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged HNF1A is 0.03 ng/ml as a capture antibody.ELISA
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Gene Info — HNF1A
Entrez GeneID
6927GeneBank Accession#
P20823Protein Accession#
P20823Gene Name
HNF1A
Gene Alias
HNF1, LFB1, MODY3, TCF1
Gene Description
HNF1 homeobox A
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. [provided by RefSeq
Other Designations
Interferon production regulator factor (HNF1)|albumin proximal factor|hepatic nuclear factor 1|maturity onset diabetes of the young 3|transcription factor 1, hepatic|transcription factor 1, hepatic; LF-B1, hepatic nuclear factor (HNF1), albumin proximal f
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Interactome
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Pathway
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Disease
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