TCF4 monoclonal antibody (M04), clone 3H4
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More Files
- More Functions
Western Blot (Cell lysate)
TCF4 monoclonal antibody (M04), clone 3H4 Western Blot analysis of TCF4 expression in A-549 ( Cat # L025V1 ).
Immunofluorescence
Immunofluorescence of monoclonal antibody to TCF4 on HeLa cell. [antibody concentration 10 ug/ml]
Western Blot detection against Immunogen (65.89 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant TCF4.
Immunogen
TCF4 (AAH31056.1, 1 a.a. ~ 365 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MHHQQRMAALGTDKELSDLLDFSAMFSPPVSSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHTTSRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRN
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (98)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (65.89 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
TCF4 monoclonal antibody (M04), clone 3H4 Western Blot analysis of TCF4 expression in A-549 ( Cat # L025V1 ).Western Blot (Recombinant protein)
ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to TCF4 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — TCF4
Entrez GeneID
6925GeneBank Accession#
BC031056.1Protein Accession#
AAH31056.1Gene Name
TCF4
Gene Alias
E2-2, ITF2, MGC149723, MGC149724, PTHS, SEF2, SEF2-1, SEF2-1A, SEF2-1B, bHLHb19
Gene Description
transcription factor 4
Gene Ontology
HyperlinkGene Summary
This gene encodes transcription factor 4, a basic helix-turn-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is expressed predominantly in pre-B-cells, although it is found in other tissues as well. Defects in this gene are a cause of Pitt-Hopkins syndrome. Multiple alternatively spliced transcript variants that encode different proteins have been described. [provided by RefSeq
Other Designations
immunoglobulin transcription factor 2
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Interactome
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Disease
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Publication Reference
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Polygonum cuspidatum Extract (Pc-Ex) Containing Emodin Suppresses Lung Cancer-Induced Cachexia by Suppressing TCF4/TWIST1 Complex-Induced PTHrP Expression.
Xue-Quan Fang, Young-Seon Kim, Yoon-Mi Lee, Mingyu Lee, Woo-Jin Lim, Woo-Jong Yim, Min-Woo Han, Ji-Hong Lim.
Nutrients 2022 Apr; 14(7):1508.
Application：WB, Human, A549, Calu-1, NCI-H358 cells.
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Polygonum cuspidatum Extract (Pc-Ex) Containing Emodin Suppresses Lung Cancer-Induced Cachexia by Suppressing TCF4/TWIST1 Complex-Induced PTHrP Expression.
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