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TCEB2 Pre-design Chimera RNAi

  • Catalog # : H00006923-R02
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  • Specification
  • Product Description:
  • Homo sapiens transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) (TCEB2), transcript variant 2, mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_207013
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 6923
  • Gene Name:
  • TCEB2
  • Gene Alias:
  • ELOB,SIII
  • Gene Description:
  • transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
  • Gene Summary:
  • This gene encodes the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. Pseudogenes have been identified on chromosomes 11 and 13. [provided by RefSeq
  • Other Designations:
  • RNA polymerase II transcription factor SIII p18 subunit,SIII p18,elongin B,elongin, 18-kD subunit,transcription elongation factor B (SIII), polypeptide 2 (18kD, elongin B)
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