Products

Enzyme-linked Immunoabsorbent Assay

Western Blot (Recombinant protein)

Antibody Production

Protein Array

Entrez GeneID

GeneBank Accession#

Protein Accession#

Gene Name

TCEB1

Gene Alias

SIII

Gene Description

transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)

Omim ID

Gene Ontology

Gene Summary

This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. [provided by RefSeq

Other Designations

elongin C|transcription elongation factor B (SIII), polypeptide 1 (15kD, elongin C)|transcription elongation factor B, polypeptide 1