TCEB1 polyclonal antibody (A01)
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length recombinant TCEB1.
Immunogen
TCEB1 (AAH13809, 1 a.a. ~ 112 a.a) full-length recombinant protein with GST tag.
Sequence
MDGEEKTYGGCEGPDAMYVKLISSDGHEFIVKREHALTSGTIKAMLSGPGQFAENETNEVNFREIPSHVLSKVCMYFTYKVRYTNSSTEIPEFPIAPEIALELLMAANFLDC
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (38.43 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — TCEB1
Entrez GeneID
6921GeneBank Accession#
BC013809Protein Accession#
AAH13809Gene Name
TCEB1
Gene Alias
SIII
Gene Description
transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
Omim ID
600788Gene Ontology
HyperlinkGene Summary
This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. [provided by RefSeq
Other Designations
elongin C|transcription elongation factor B (SIII), polypeptide 1 (15kD, elongin C)|transcription elongation factor B, polypeptide 1
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Interactome
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