TBXAS1 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-TBXAS1 full-length
Host
Human
Theoretical MW (kDa)
60.6
Interspecies Antigen Sequence
Mouse (82); Rat (80)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-TBXAS1 antibody (H00006916-B01) by Western Blots.
SDS-PAGE Gel
TBXAS1 transfected lysate.
Western Blot
Lane 1: TBXAS1 transfected lysate ( 60.6 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — TBXAS1
Entrez GeneID
6916GeneBank Accession#
BC041157.1Protein Accession#
-Gene Name
TBXAS1
Gene Alias
CYP5, CYP5A1, GHOSAL, THAS, TS, TXAS, TXS
Gene Description
thromboxane A synthase 1 (platelet)
Omim ID
274180Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
TXA synthase|cytochrome P450, family 5, subfamily A, polypeptide 1|platelet, cytochrome P450, subfamily V|thromboxane A synthase 1
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