Products

Western Blot (Transfected lysate)

Entrez GeneID

GeneBank Accession#

Protein Accession#

Gene Name

TARBP1

Gene Alias

FLJ30482, TRM3, TRP-185, TRP185

Gene Description

TAR (HIV-1) RNA binding protein 1

Omim ID

Gene Ontology

Gene Summary

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. This element forms a stable stem-loop structure and can be bound by either the protein encoded by this gene or by RNA polymerase II. This protein may act to disengage RNA polymerase II from TAR during transcriptional elongation. Alternatively spliced transcripts of this gene may exist, but their full-length natures have not been determined. [provided by RefSeq

Other Designations

OTTHUMP00000036048|TAR (HIV) RNA binding protein 1|TAR (HIV) RNA-binding protein 1|TAR RNA binding protein 1|TAR RNA loop binding protein