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TAP2 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00006891-T02
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-TAP2 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 75.7
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-TAP2antibody (H00006891-D01P)byWesternBlots.
    SDS-PAGE Gel
    QC Testing of H00006891-T02
    TAP2 transfected lysate.
    Western Blot
    QC Testing of H00006891-T02
    Lane 1: TAP2 transfected lysate ( 75.7 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 6891
  • Gene Name:
  • TAP2
  • Gene Alias:
  • ABC18,ABCB3,APT2,D6S217E,PSF2,RING11
  • Gene Description:
  • transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
  • Gene Summary:
  • The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Alternative splicing of this gene produces two products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules. [provided by RefSeq
  • Other Designations:
  • ABC transporter, MHC 2,ATP-binding cassette, sub-family B (MDR/TAP), member 3,OTTHUMP00000029079,OTTHUMP00000038912,OTTHUMP00000038914,antigen peptide transporter 2,peptide supply factor 2,peptide transporter PSF2,transporter 2, ABC (ATP binding cassette)
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