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Last updated: 2017/6/18

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TAP2 rabbit monoclonal antibody

  • Catalog # : H00006891-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human TAP2 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human TAP2 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human TAP2 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 6891
  • GeneBank Accession#:
  • TAP2
  • Gene Name:
  • TAP2
  • Gene Alias:
  • ABC18,ABCB3,APT2,D6S217E,PSF2,RING11
  • Gene Description:
  • transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
  • Gene Summary:
  • The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Alternative splicing of this gene produces two products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules. [provided by RefSeq
  • Other Designations:
  • ABC transporter, MHC 2,ATP-binding cassette, sub-family B (MDR/TAP), member 3,OTTHUMP00000029079,OTTHUMP00000038912,OTTHUMP00000038914,antigen peptide transporter 2,peptide supply factor 2,peptide transporter PSF2,transporter 2, ABC (ATP binding cassette)
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