MAP3K7 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
MAP3K7 transfected lysate.
Western Blot
Lane 1: MAP3K7 transfected lysate ( 63.8 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-MAP3K7 full-length
Host
Human
Theoretical MW (kDa)
63.8
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-MAP3K7 antibody (H00006885-B01) by Western Blots.
SDS-PAGE Gel
MAP3K7 transfected lysate.
Western Blot
Lane 1: MAP3K7 transfected lysate ( 63.8 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — MAP3K7
Entrez GeneID
6885GeneBank Accession#
NM_003188.2Protein Accession#
NP_003179.1Gene Name
MAP3K7
Gene Alias
TAK1, TGF1a
Gene Description
mitogen-activated protein kinase kinase kinase 7
Omim ID
602614Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq
Other Designations
OTTHUMP00000016870|OTTHUMP00000016871|OTTHUMP00000016872|OTTHUMP00000016873|TGF-beta activated kinase 1|transforming growth factor-beta-activated kinase 1
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Interactome
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Pathway
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Disease
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