MAP3K7 (Human) IP-WB Antibody Pair
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More Files
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Immunoprecipitation of MAP3K7 transfected lysate using rabbit polyclonal anti-MAP3K7 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-MAP3K7.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of MAP3K7 transfected lysate using rabbit polyclonal anti-MAP3K7 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-MAP3K7.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-MAP3K7 (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-MAP3K7 (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — MAP3K7
Entrez GeneID
6885Gene Name
MAP3K7
Gene Alias
TAK1, TGF1a
Gene Description
mitogen-activated protein kinase kinase kinase 7
Omim ID
602614Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq
Other Designations
OTTHUMP00000016870|OTTHUMP00000016871|OTTHUMP00000016872|OTTHUMP00000016873|TGF-beta activated kinase 1|transforming growth factor-beta-activated kinase 1
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Interactome
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Disease
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