MAP3K7 MaxPab rabbit polyclonal antibody (D01)
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More Files
- More Functions
Western Blot (Cell lysate)
MAP3K7 MaxPab rabbit polyclonal antibody. Western Blot analysis of MAP3K7 expression in A-431.
Western Blot (Transfected lysate)
Western Blot analysis of MAP3K7 expression in transfected 293T cell line (H00006885-T02) by MAP3K7 MaxPab polyclonal antibody.
Lane 1: MAP3K7 transfected lysate(64.20 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of MAP3K7 transfected lysate using anti-MAP3K7 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with MAP3K7 purified MaxPab mouse polyclonal antibody (B01P) (H00006885-B01P).
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to MAP3K7 on HeLa cell. [antibody concentration 30 ug/ml]
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human MAP3K7 protein.
Immunogen
MAP3K7 (NP_003179.1, 1 a.a. ~ 579 a.a) full-length human protein.
Sequence
MSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAFIVELRQLSRVNHPNIVKLYGACLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTACDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPGADEPLQYPCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPATNDTIKRLESKLLKNQAKQQSESGRLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIAATTGNGQPRRRSIQDLTVTGTEPGQVSSRSSSPSVRMITTSGPTSEKPTRSHPWTPDDSTDTNGSDNSIPMAYLTLDHQLQPLAPCPNSKESMAVFEQHCKMAQEYMKVQTEIALLLQRKQELVAELDQDEKDQQNTSRLVQEHKKLLDENKSLSTYYQQCKKQLEVIRSQQQKRQGTS
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
MAP3K7 MaxPab rabbit polyclonal antibody. Western Blot analysis of MAP3K7 expression in A-431.Western Blot (Transfected lysate)
Western Blot analysis of MAP3K7 expression in transfected 293T cell line (H00006885-T02) by MAP3K7 MaxPab polyclonal antibody.
Lane 1: MAP3K7 transfected lysate(64.20 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of MAP3K7 transfected lysate using anti-MAP3K7 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with MAP3K7 purified MaxPab mouse polyclonal antibody (B01P) (H00006885-B01P).Immunofluorescence
Immunofluorescence of purified MaxPab antibody to MAP3K7 on HeLa cell. [antibody concentration 30 ug/ml] -
Gene Info — MAP3K7
Entrez GeneID
6885GeneBank Accession#
NM_003188.2Protein Accession#
NP_003179.1Gene Name
MAP3K7
Gene Alias
TAK1, TGF1a
Gene Description
mitogen-activated protein kinase kinase kinase 7
Omim ID
602614Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq
Other Designations
OTTHUMP00000016870|OTTHUMP00000016871|OTTHUMP00000016872|OTTHUMP00000016873|TGF-beta activated kinase 1|transforming growth factor-beta-activated kinase 1
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Interactome
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Pathway
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Disease
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