VAMP2 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human VAMP2 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MSATAATAPPAAPAGEGGPPAPPPNLTSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNLKMMIILGVICAIILIIIIVYFST
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — VAMP2
Entrez GeneID
6844GeneBank Accession#
BC019608Protein Accession#
no protein_accGene Name
VAMP2
Gene Alias
FLJ11460, SYB2, VAMP-2
Gene Description
vesicle-associated membrane protein 2 (synaptobrevin 2)
Omim ID
185881Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG. [provided by RefSeq
Other Designations
synaptobrevin 2|vesicle associated membrane protein 2
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Interactome
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Pathway
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Disease
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