SUV39H1 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human SUV39H1 full-length ORF ( AAH06238.1, 1 a.a. - 412 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MAENLKGCSVCCKSSWNQLQDLCRLAKLSCPALGISKRNLYDFEVEYLCDYKKIREQEYYLVKWRGYPDSESTWEPRQNLKCVRILKQFHKDLERELLRRHHRSKTPRHLDPSLANYLVQKAKQRRALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINEYRVGEGITLNQVAVGCECQDCLWAPTGGCCPGASLHKFAYNDQGQVRLRAGLPIYECNSRCRCGYDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFDLDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRKYLF
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
74.3
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — SUV39H1
Entrez GeneID
6839GeneBank Accession#
BC006238.2Protein Accession#
AAH06238.1Gene Name
SUV39H1
Gene Alias
KMT1A, MG44, SUV39H
Gene Description
suppressor of variegation 3-9 homolog 1 (Drosophila)
Omim ID
300254Gene Ontology
HyperlinkGene Summary
This gene is a member of the suppressor of variegation 3-9 homolog family and encodes a protein with a chromodomain and a C-terminal SET domain. This nuclear protein moves to the centromeres during mitosis and functions as a histone methyltransferase, methylating Lys-9 of histone H3. Overall, it plays a vital role in heterochromatin organization, chromosome segregation, and mitotic progression. [provided by RefSeq
Other Designations
H3-K9-HMTase 1|OTTHUMP00000024298|Su(var)3-9 homolog 1|histone H3-K9 methyltransferase 1|histone-lysine N-methyltransferase, H3 lysine-9 specific 1|suppressor of variegation 3-9 homolog 1
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Interactome
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Pathway
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