SUV39H1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human SUV39H1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human SUV39H1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human SUV39H1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — SUV39H1
Entrez GeneID
6839GeneBank Accession#
SUV39H1Gene Name
SUV39H1
Gene Alias
KMT1A, MG44, SUV39H
Gene Description
suppressor of variegation 3-9 homolog 1 (Drosophila)
Omim ID
300254Gene Ontology
HyperlinkGene Summary
This gene is a member of the suppressor of variegation 3-9 homolog family and encodes a protein with a chromodomain and a C-terminal SET domain. This nuclear protein moves to the centromeres during mitosis and functions as a histone methyltransferase, methylating Lys-9 of histone H3. Overall, it plays a vital role in heterochromatin organization, chromosome segregation, and mitotic progression. [provided by RefSeq
Other Designations
H3-K9-HMTase 1|OTTHUMP00000024298|Su(var)3-9 homolog 1|histone H3-K9 methyltransferase 1|histone-lysine N-methyltransferase, H3 lysine-9 specific 1|suppressor of variegation 3-9 homolog 1
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Interactome
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Pathway
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