This antibody pair set comes with matched antibody pair to detect and quantify protein level of human STX1A.
Quality Control Testing:
Standard curve using recombinant protein ( H00006804-P01 ) as an analyte.
Sandwich ELISA detection sensitivity ranging from 0.1 ng/ml to 100 ng/ml.
Antibody pair set content: 1. Capture antibody: rabbit MaxPab® affinity purified polyclonal anti-STX1A (100 ug) 2. Detection antibody: mouse polyclonal anti-STX1A (40 ul) *Reagents are sufficient for at least 3-5 x 96 well plates using recommended protocols.
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
Synaptic vesicles store neurotransmitters that are released during calcium-regulated exocytosis. The specificity of neurotransmitter release requires the localization of both synaptic vesicles and calcium channels to the presynaptic active zone. Syntaxins function in this vesicle fusion process. Syntaxins also serve as a substrate for botulinum neurotoxin type C, a metalloprotease that blocks exocytosis and has high affinity for a molecular complex that includes the alpha-latrotoxin receptor (MIM 600565) which produces explosive exocytosis (Zhang et al., 1995 [PubMed 7622072]).[supplied by OMIM