STAU1 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
- More Functions
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-STAU1 full-length
Host
Human
Theoretical MW (kDa)
63.58
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-STAU1 antibody (H00006780-B01) by Western Blots.
Western Blot
Lane 1: STAU1 transfected lysate ( 63.2 KDa)
Lane 2: Non-transfected lysate.SDS-PAGE Gel
STAU1 transfected lysate.
Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — STAU1
Entrez GeneID
6780GeneBank Accession#
NM_017453.2Protein Accession#
-Gene Name
STAU1
Gene Alias
FLJ25010, STAU
Gene Description
staufen, RNA binding protein, homolog 1 (Drosophila)
Omim ID
601716Gene Ontology
HyperlinkGene Summary
Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the same isoform, however, differ in their 5'UTR. [provided by RefSeq
Other Designations
OTTHUMP00000031233|OTTHUMP00000031234|OTTHUMP00000031235|OTTHUMP00000031236|OTTHUMP00000031238|staufen
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