STAT6 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Western Blot (Tissue lysate)
STAT6 MaxPab polyclonal antibody. Western Blot analysis of STAT6 expression in human pancreas.
Western Blot (Transfected lysate)
Western Blot analysis of STAT6 expression in transfected 293T cell line (H00006778-T01) by STAT6 MaxPab polyclonal antibody.
Lane 1: STAT6 transfected lysate(93.17 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to STAT6 on HeLa cell. [antibody concentration 10 ug/ml]
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human STAT6 protein.
Immunogen
STAT6 (NP_003144.3, 1 a.a. ~ 847 a.a) full-length human protein.
Sequence
MSLWGLVSKMPPEKVQRLYVDFPQHLRHLLGDWLESQPWEFLVGSDAFCCNLASALLSDTVQHLQASVGEQGEGSTILQHISTLESIYQRDPLKLVATFRQILQGEKKAVMEQFRHLPMPFHWKQEELKFKTGLRRLQHRVGEIHLLREALQKGAEAGQVSLHSLIETPANGTGPSEALAMLLQETTGELEAAKALVLKRIQIWKRQQQLAGNGAPFEESLAPLQERCESLVDIYSQLQQEVGAAGGELEPKTRASLTGRLDEVLRTLVTSCFLVEKQPPQVLKTQTKFQAGVRFLLGLRFLGAPAKPPLVRADMVTEKQARELSVPQGPGAGAESTGEIINNTVPLENSIPGNCCSALFKNLLLKKIKRCERKGTESVTEEKCAVLFSASFTLGPGKLPIQLQALSLPLVVIVHGNQDNNAKATILWDNAFSEMDRVPFVVAERVPWEKMCETLNLKFMAEVGTNRGLLPEHFLFLAQKIFNDNSLSMEAFQHRSVSWSQFNKEILLGRGFTFWQWFDGVLDLTKRCLRSYWSDRLIIGFISKQYVTSLLLNEPDGTFLLRFSDSEIGGITIAHVIRGQDGSPQIENIQPFSAKDLSIRSLGDRIRDLAQLKNLYPKKPKDEAFRSHYKPEQMGKDGRGYVPATIKMTVERDQPLPTPELQMPTMVPSYDLGMAPDSSMSMQLGPDMVPQVYPPHSHSIPPYQGLSPEESVNVLSAFQEPHLQMPPSLGQMSLPFDQPHPQGLLPCQPQEHAVSSPDPLLCSDVTMVEDSCLSQPVTAFPQGTWIGEDIFPPLLPPTEQDLTKLLLEGQGESGGGSLGAQPLLQPSHYGQSGISMSHMDLRANPSW
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
STAT6 MaxPab polyclonal antibody. Western Blot analysis of STAT6 expression in human pancreas.Western Blot (Transfected lysate)
Western Blot analysis of STAT6 expression in transfected 293T cell line (H00006778-T01) by STAT6 MaxPab polyclonal antibody.
Lane 1: STAT6 transfected lysate(93.17 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to STAT6 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — STAT6
Entrez GeneID
6778GeneBank Accession#
NM_003153.3Protein Accession#
NP_003144.3Gene Name
STAT6
Gene Alias
D12S1644, IL-4-STAT, STAT6B, STAT6C
Gene Description
signal transducer and activator of transcription 6, interleukin-4 induced
Omim ID
601512Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. [provided by RefSeq
Other Designations
STAT, interleukin4-induced|signal transducer and activator of transcription 6|transcription factor IL-4 STAT
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Interactome
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Pathway
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Disease
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