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STAT5B 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00006777-T01
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-STAT5B full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 44.9
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-STAT5B antibody (H00006777-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00006777-T01
    STAT5B transfected lysate.
    Western Blot
    QC Testing of H00006777-T01
    Lane 1: STAT5B transfected lysate ( 44.9 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 6777
  • Protein Accession#:
  • -
  • Gene Name:
  • STAT5B
  • Gene Alias:
  • STAT5
  • Gene Description:
  • signal transducer and activator of transcription 5B
  • Gene Summary:
  • The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. [provided by RefSeq
  • Other Designations:
  • transcription factor STAT5B
  • Interactome
  • Interactome
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