STAT5B (Human) IP-WB Antibody Pair

Catalog # H00006777-PW1

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Size:1 Set
Price: USD $ 607.00
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  • +1-909-264-1399
    +1-909-992-0619
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  • +1-909-992-3401
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Immunoprecipitation of STAT5B transfected lysate using mouse monoclonal anti-STAT5B and Protein A Magnetic Bead (U0007), and immunoblotted with mouse monoclonal anti-STAT5B.

  • Specification

    Product Description

    This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.

    Reactivity

    Human

    Quality Control Testing

    Immunoprecipitation-Western Blot (IP-WB)

    Immunoprecipitation of STAT5B transfected lysate using mouse monoclonal anti-STAT5B and Protein A Magnetic Bead (U0007), and immunoblotted with mouse monoclonal anti-STAT5B.

    Supplied Product

    Antibody pair set content:
    1. Antibody pair for IP: mouse monoclonal anti-STAT5B (300 ug)
    2. Antibody pair for WB: mouse monoclonal anti-STAT5B (50 ug)

    Storage Instruction

    Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.

  • Applications

    Immunoprecipitation-Western Blot

  • Gene Info — STAT5B

    Entrez GeneID

    6777

    Gene Name

    STAT5B

    Gene Alias

    STAT5

    Gene Description

    signal transducer and activator of transcription 5B

    Omim ID

    245590 604260

    Gene Ontology

    Hyperlink

    Gene Summary

    The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. [provided by RefSeq

    Other Designations

    transcription factor STAT5B

  • Interactome
  • Pathway
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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