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ST14 rabbit monoclonal antibody

  • Catalog # : H00006768-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human ST14 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human ST14 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human ST14 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 6768
  • GeneBank Accession#:
  • ST14
  • Gene Name:
  • ST14
  • Gene Alias:
  • HAI,MT-SP1,MTSP-1,MTSP1,PRSS14,SNC19,TADG-15
  • Gene Description:
  • suppression of tumorigenicity 14 (colon carcinoma)
  • Gene Summary:
  • The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis. [provided by RefSeq
  • Other Designations:
  • epithin,matriptase,membrane-type serine protease,serine protease TADG-15,suppression of tumorigenicity 14,suppression of tumorigenicity 14 (colon carcinoma, matriptase, epithin),tumor associated differentially expressed gene 15 protein
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