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ST5 Pre-design Chimera RNAi

  • Catalog # : H00006764-R01
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  • Specification
  • Product Description:
  • Homo sapiens suppression of tumorigenicity 5 (ST5), transcript variant 1, mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_005418
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 6764
  • Gene Name:
  • ST5
  • Gene Alias:
  • DENND2B,HTS1,MGC33090,p126
  • Gene Description:
  • suppression of tumorigenicity 5
  • Gene Summary:
  • This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified. [provided by RefSeq
  • Other Designations:
  • DENN/MADD domain containing 2B
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