SSX5 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human SSX5 protein.
Immunogen
SSX5 (AAH16640.1, 1 a.a. ~ 229 a.a) full-length human protein.
Sequence
MNGDDAFVRRPRVGSQIPQKMQKHPWRQVCDRGIHLVNLSPFWKVGREPASSIKALLCGRGEARAFDDIAKYFSEKEWEKMKASEKIIYVYMKRKYEAMTKLGFKATLPPFMRNKRVADFQGNDFDNDPNRGNQVEHPQMTFGRLQGIFPKITPEKPAEEGNDSKGVPEASGPQNNGKQLRPSGKLNTSEKVNKTSGPKRGKHAWTHRVRERKQLVIYEEISDPQEDDE
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of SSX5 expression in transfected 293T cell line (H00006758-T01) by SSX5 MaxPab polyclonal antibody.
Lane 1: SSX5 transfected lysate(25.19 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to SSX5 on HepG2 cell. [antibody concentration 10 ug/ml] -
Gene Info — SSX5
Entrez GeneID
6758GeneBank Accession#
BC016640.2Protein Accession#
AAH16640.1Gene Name
SSX5
Gene Alias
MGC9494
Gene Description
synovial sarcoma, X breakpoint 5
Omim ID
300327Gene Ontology
HyperlinkGene Summary
The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This gene appears not to be involved in this type of chromosome translocation. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000023239|OTTHUMP00000023240
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Interactome
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Publication Reference
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Expression and Immunotherapeutic Targeting of the SSX Family of Cancer-Testis Antigens in Prostate Cancer.
Smith HA, Cronk RJ, Lang JM, McNeel DG.
Cancer Research 2011 Nov; 71(21):6785.
Application:IHC-P, WB-Re, Human, Human testis tissues.
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Expression and Immunotherapeutic Targeting of the SSX Family of Cancer-Testis Antigens in Prostate Cancer.
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