SSX2 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-SSX2 full-length
Host
Human
Theoretical MW (kDa)
23.2
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-SSX2 antibody (H00006757-B03) by Western Blots.
Western Blot
Lane 1: SSX2 transfected lysate ( 25.2 KDa)
Lane 2: Non-transfected lysate.SDS-PAGE Gel
SSX2 transfected lysate.
Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — SSX2
Entrez GeneID
6757GeneBank Accession#
NM_003147Protein Accession#
NP_003138Gene Name
SSX2
Gene Alias
HD21, HOM-MEL-40, MGC119055, MGC15364, MGC3884, SSX
Gene Description
synovial sarcoma, X breakpoint 2
Omim ID
300192Gene Ontology
HyperlinkGene Summary
The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000024290|OTTHUMP00000024291|sarcoma, synovial, X-chromosome-related 2|synovial sarcoma, X breakpoint 2, isoform b|synovial sarcoma, X breakpoint 2B
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