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SSRP1 (Human) Recombinant Protein (P01)

  • Catalog # : H00006749-P01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Human SSRP1 full-length ORF ( NP_003137.1, 1 a.a. - 709 a.a.) recombinant protein with GST-tag at N-terminal.
  • Sequence:
  • Host:
  • Wheat Germ (in vitro)
  • Theoretical MW (kDa):
  • 107.5
  • Purification:
  • Glutathione Sepharose 4 Fast Flow
  • Quality Control Testing:
  • 12.5% SDS-PAGE Stained with Coomassie Blue.

    QC Testing of H00006749-P01
  • Storage Buffer:
  • 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Best use within three months from the date of receipt of this protein.
  • Applications
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Application Image
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Gene Information
  • Entrez GeneID:
  • 6749
  • Gene Name:
  • SSRP1
  • Gene Alias:
  • FACT,FACT80,T160
  • Gene Description:
  • structure specific recognition protein 1
  • Gene Summary:
  • The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known. [provided by RefSeq
  • Other Designations:
  • chromatin-specific transcription elongation factor 80 kDa subunit,cisplatin-DNA SSRP,facilitates chromatin remodeling 80 kDa subunit,high mobility group box,recombination signal sequence recognition protein
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