SSR4 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human SSR4 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MAAMASLGALALLLLSSLSRCSAEACLEPQITPSYYTTSDAVISTETVFIVEISLTCKNRVQNMALYADVGGKQFPVTRGQDVGRYQVSWSLDHKSAHAGTYEVRFFDEESYSLLRKAQRNNEDISIIPPLFTVSVDHRGTWNGPWVSTEVLAAAIGLVIYYLAFSAKSHIQA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — SSR4
Entrez GeneID
6748GeneBank Accession#
NM_006280.1Protein Accession#
NP_006271.1Gene Name
SSR4
Gene Alias
TRAPD
Gene Description
signal sequence receptor, delta (translocon-associated protein delta)
Omim ID
300090Gene Ontology
HyperlinkGene Summary
SSR4, also called TRAPD, is assumed to be involved in protein secretion. It is located in the Xq28 region, arranged in a compact head-to-head manner with the IDH3G gene. These two genes are driven by a bidirectional promoter located between them, and encode proteins involved in unrelated biochemical pathways located in different compartments of the cell. The nontranscribed intergenic region represents only 133 bp and is embedded in a CpG island. The CpG island functions as a bidirectional promoter to initiate the transcription of both functionally unrelated genes with distinct expression patterns. SSR4 consists of six exons and is approximately 70 kb telomeric to the ALD gene. Although alternative splicing of exon 5 has not been detected in human SSR4, transcript variants missing the region homologous to human exon 5 have been detected in both Xenopus laevis and Mus musculus. [provided by RefSeq
Other Designations
OTTHUMP00000025956|OTTHUMP00000025957|OTTHUMP00000025958|signal sequence receptor, delta|translocon-associated protein delta
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