SRF monoclonal antibody (M05), clone 4D2
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More Files
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Western Blot (Cell lysate)
SRF monoclonal antibody (M05), clone 4D2. Western Blot analysis of SRF expression in Hela S3 NE ( Cat # L013V3 ).
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant SRF.
Immunogen
SRF (NP_003122, 244 a.a. ~ 332 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
TDLTYQVSESDSSGETKDTLKPAFTVTNLPGTTSTIQTAPSTSTTMQVSSGPSFPITNYLAPVSASVSPSAVSSANGTVLKSTGSGPV
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (100); Rat (100)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
SRF monoclonal antibody (M05), clone 4D2. Western Blot analysis of SRF expression in Hela S3 NE ( Cat # L013V3 ).ELISA
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Gene Info — SRF
Entrez GeneID
6722GeneBank Accession#
NM_003131Protein Accession#
NP_003122Gene Name
SRF
Gene Alias
MCM1
Gene Description
serum response factor (c-fos serum response element-binding transcription factor)
Omim ID
600589Gene Ontology
HyperlinkGene Summary
This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). [provided by RefSeq
Other Designations
OTTHUMP00000039820
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Interactome
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Pathway
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Disease
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