AKR1D1 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human AKR1D1 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MDLSAASHRIPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNKNVRFVELLMWRDHPEYPFHDEY
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — AKR1D1
Entrez GeneID
6718GeneBank Accession#
NM_005989.2Protein Accession#
NP_005980.1Gene Name
AKR1D1
Gene Alias
3o5bred, SRD5B1
Gene Description
aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)
Omim ID
604741Gene Ontology
HyperlinkGene Summary
The enzyme encoded by this gene is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure. Deficiency of this enzyme may contribute to hepatic dysfunction. [provided by RefSeq
Other Designations
aldo-keto reductase family 1, member D1|steroid 5-beta-reductase|steroid-5-beta-reductase, beta polypeptide 1 (3-oxo-5 beta-steroid delta 4-dehydrogenase beta 1)
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Interactome
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Pathway
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Disease
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