AKR1D1 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human AKR1D1 protein.
Immunogen
AKR1D1 (NP_005980.1, 1 a.a. ~ 326 a.a) full-length human protein.
Sequence
MDLSAASHRIPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNKNVRFVELLMWRDHPEYPFHDEY
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
AKR1D1 MaxPab polyclonal antibody. Western Blot analysis of AKR1D1 expression in human liver.Western Blot (Transfected lysate)
Western Blot analysis of AKR1D1 expression in transfected 293T cell line (H00006718-T01) by AKR1D1 MaxPab polyclonal antibody.
Lane1:AKR1D1 transfected lysate(35.86 KDa).
Lane2:Non-transfected lysate.
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Gene Info — AKR1D1
Entrez GeneID
6718GeneBank Accession#
NM_005989.2Protein Accession#
NP_005980.1Gene Name
AKR1D1
Gene Alias
3o5bred, SRD5B1
Gene Description
aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)
Omim ID
604741Gene Ontology
HyperlinkGene Summary
The enzyme encoded by this gene is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure. Deficiency of this enzyme may contribute to hepatic dysfunction. [provided by RefSeq
Other Designations
aldo-keto reductase family 1, member D1|steroid 5-beta-reductase|steroid-5-beta-reductase, beta polypeptide 1 (3-oxo-5 beta-steroid delta 4-dehydrogenase beta 1)
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Interactome
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Pathway
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Disease
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