SRD5A1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human SRD5A1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human SRD5A1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human SRD5A1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — SRD5A1
Entrez GeneID
6715GeneBank Accession#
SRD5A1Gene Name
SRD5A1
Gene Alias
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Gene Description
steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
Omim ID
184753Gene Ontology
HyperlinkGene Summary
Steroid 5-alpha-reductase (EC 1.3.99.5) catalyzes the conversion of testosterone into the more potent androgen, dihydrotestosterone (DHT). Also see SRD5A2 (MIM 607306).[supplied by OMIM
Other Designations
3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1|5-alpha reductase|OTTHUMP00000115519|steroid 5-alpha-reductase type I|steroid-5-alpha-reductase 1
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