Rabbit monoclonal antibody raised against a human SRC peptide using ARM Technology.
Immunogen:
A synthetic peptide of human SRC is used for rabbit immunization. Customer or Abnova will decide on the preferred peptide sequence.
Host:
Rabbit
Reactivity:
Human
Purification:
Protein A
Isotype:
IgG
Quality Control Testing:
Antibody reactive against human SRC peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer:
In 1x PBS, pH 7.4
Storage Instruction:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note:
1. Customer may provide cell or tissue lysate for antibody screening. 2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
Library Construction:
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression:
Overexpression vector and transfection into 293H cell line.
Deliverable:
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq