SPR 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-SPR full-length
Host
Human
Theoretical MW (kDa)
28.82
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-SPR antibody (H00006697-B01) by Western Blots.
SDS-PAGE Gel
SPR transfected lysate.
Western Blot
Lane 1: SPR transfected lysate ( 28.82 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — SPR
Entrez GeneID
6697GeneBank Accession#
NM_003124.3Protein Accession#
AAH17310.1Gene Name
SPR
Gene Alias
SDR38C1
Gene Description
sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
Omim ID
182125Gene Ontology
HyperlinkGene Summary
This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1. [provided by RefSeq
Other Designations
short chain dehydrogenase/reductase family 38C, member 1
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Interactome
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Pathway
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Disease
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