SPR (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human SPR partial ORF ( NP_003115, 164 a.a. - 260 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
FKGWALYCAGKAARDMLFQVLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLEKDEFKSGAHVDFYD
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.41
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — SPR
Entrez GeneID
6697GeneBank Accession#
NM_003124Protein Accession#
NP_003115Gene Name
SPR
Gene Alias
SDR38C1
Gene Description
sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
Omim ID
182125Gene Ontology
HyperlinkGene Summary
This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1. [provided by RefSeq
Other Designations
short chain dehydrogenase/reductase family 38C, member 1
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Interactome
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Pathway
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Disease
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