SPR rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human SPR peptide using ARM Technology.
Immunogen
A synthetic peptide of human SPR is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human SPR peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — SPR
Entrez GeneID
6697GeneBank Accession#
SPRGene Name
SPR
Gene Alias
SDR38C1
Gene Description
sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
Omim ID
182125Gene Ontology
HyperlinkGene Summary
This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1. [provided by RefSeq
Other Designations
short chain dehydrogenase/reductase family 38C, member 1
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Interactome
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