SPR polyclonal antibody (A01)
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Cell lysate)
SPR polyclonal antibody (A01), Lot # 060814QCS1. Western Blot analysis of SPR expression in Jurkat.
Western Blot (Cell lysate)
SPR polyclonal antibody (A01), Lot # 060123JCO1 Western Blot analysis of SPR expression in A-431 ( Cat # L015V1 ).
Western Blot detection against Immunogen (36.78 KDa) .
-
Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant SPR.
Immunogen
SPR (NP_003115, 164 a.a. ~ 260 a.a) partial recombinant protein with GST tag.
Sequence
FKGWALYCAGKAARDMLFQVLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLEKDEFKSGAHVDFYD
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.78 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
-
Applications
Western Blot (Cell lysate)
SPR polyclonal antibody (A01), Lot # 060814QCS1. Western Blot analysis of SPR expression in Jurkat.Western Blot (Cell lysate)
SPR polyclonal antibody (A01), Lot # 060123JCO1 Western Blot analysis of SPR expression in A-431 ( Cat # L015V1 ).Western Blot (Recombinant protein)
ELISA
-
Gene Info — SPR
Entrez GeneID
6697GeneBank Accession#
NM_003124Protein Accession#
NP_003115Gene Name
SPR
Gene Alias
SDR38C1
Gene Description
sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
Omim ID
182125Gene Ontology
HyperlinkGene Summary
This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1. [provided by RefSeq
Other Designations
short chain dehydrogenase/reductase family 38C, member 1
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
Valproic acid exposure leads to upregulation and increased promoter histone acetylation of sepiapterin reductase in a serotonergic cell line.
Balasubramanian D, Deng AX, Doudney K, Hampton MB, Kennedy MA.
Neuropharmacology 2015 Dec; 99:79.
Application：WB, Rat, RN46A cells.
-
Valproic acid exposure leads to upregulation and increased promoter histone acetylation of sepiapterin reductase in a serotonergic cell line.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com