SPINK1 (Human) Matched Antibody Pair
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Specification
Product Description
This antibody pair set comes with a matched antibody pair to detect and quantify the protein level of human SPINK1.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (68)
Quality Control Testing
Standard curve using recombinant protein ( H00006690-P01 ) as an analyte.
Sandwich ELISA detection sensitivity ranging from 1 ng/ml to 100 ng/ml.
Supplied Product
Antibody pair set content:
1. Capture antibody: mouse monoclonal anti-SPINK1, IgG2a Kappa (100 ug)
2. Detection antibody: biotinylated mouse monoclonal anti-SPINK1, IgG2b Kappa (50 ug)
*Reagents are sufficient for at least 3-5 x 96 well plates using recommended protocols.Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
ELISA Pair (Recombinant protein)
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Gene Info — SPINK1
Entrez GeneID
6690Gene Name
SPINK1
Gene Alias
PCTT, PSTI, Spink3, TATI
Gene Description
serine peptidase inhibitor, Kazal type 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis. [provided by RefSeq
Other Designations
pancreatic secretory trypsin inhibitor|serine protease inhibitor, Kazal type 1|tumor-associated trypsin inhibitor
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Interactome
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Disease
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Publication Reference
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Pancreatic secretory trypsin inhibitor causes autocrine-mediated migration & invasion in bladder cancer & phosphorylates the EGF receptor, Akt 2 & 3, ERK1 & 2.
Marchbank T, Mahmood A, Playford RJ.
American Journal of Physiology. Renal Physiology 2013 Aug; 305(3):F382.
Application:EPair-Re, Human, 253J cells.
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Pancreatic secretory trypsin inhibitor causes autocrine-mediated migration & invasion in bladder cancer & phosphorylates the EGF receptor, Akt 2 & 3, ERK1 & 2.
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