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Last updated: 2016/12/4

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SPG7 rabbit monoclonal antibody

  • Catalog # : H00006687-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human SPG7 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human SPG7 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human SPG7 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 6687
  • GeneBank Accession#:
  • SPG7
  • Gene Name:
  • SPG7
  • Gene Alias:
  • CAR,CMAR,FLJ37308,MGC126331,MGC126332,PGN,SPG5C
  • Gene Description:
  • spastic paraplegia 7 (pure and complicated autosomal recessive)
  • Gene Summary:
  • This gene encodes a nuclear-encoded mitochondrial metalloprotease protein that is a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. Two transcript variants encoding distinct isoforms have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 7. [provided by RefSeq
  • Other Designations:
  • cell adhesion regulator,cell matrix adhesion regulator,paraplegin, isoform 1,spastic paraplegia 7
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