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Last updated: 2016/11/27

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SPAST Pre-design Chimera RNAi

  • Catalog # : H00006683-R02
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  • Specification
  • Product Description:
  • Homo sapiens spastin (SPAST), transcript variant 2, mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_199436
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 6683
  • Gene Name:
  • SPAST
  • Gene Alias:
  • ADPSP,FSP2,KIAA1083,SPG4
  • Gene Description:
  • spastin
  • Gene Summary:
  • This gene encodes a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. The encoded ATPase may be involved in the assembly or function of nuclear protein complexes. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their full length sequences have not been determined. Mutations associated with this gene cause the most frequent form of autosomal dominant spastic paraplegia 4. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000158570,spastic paraplegia 4 (autosomal dominant; spastin)
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