SOX12 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of SOX12 expression in transfected 293T cell line (H00006666-T01) by SOX12 MaxPab polyclonal antibody.
Lane1:SOX12 transfected lysate(34.65 KDa).
Lane2:Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human SOX12 protein.
Immunogen
SOX12 (NP_008874.2, 1 a.a. ~ 315 a.a) full-length human protein.
Sequence
MVQQRGARAKRDGGPPPPGPGPAEEGAREPGWCKTPSGHIKRPMNAFMVWSQHERRKIMDQWPDMHNAEISKRLGRRWQLLQDSEKIPFVREAERLRLKHMADYPDYKYRPRKKSKGAPAKARPRPPGGSGGGSRLKPGPQLPGRGGRRAAGGPLGGGAAAPEDDDEDDDEELLEVRLVETPGRELWRMVPAGRAARGQAERAQGPSGEGAAAAAAASPTPSEDEEPEEEEEEAAAAEEGEEETVASGEESLGFLSRLPPGPAGLDCSALDRDPDLQPPSGTSHFEFPDYCTPEVTEMIAGDWRPSSIADLVFTY
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of SOX12 expression in transfected 293T cell line (H00006666-T01) by SOX12 MaxPab polyclonal antibody.
Lane1:SOX12 transfected lysate(34.65 KDa).
Lane2:Non-transfected lysate.
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Gene Info — SOX12
Entrez GeneID
6666GeneBank Accession#
NM_006943.2Protein Accession#
NP_008874.2Gene Name
SOX12
Gene Alias
SOX22
Gene Description
SRY (sex determining region Y)-box 12
Omim ID
601947Gene Ontology
HyperlinkGene Summary
Members of the SOX family of transcription factors are characterized by the presence of a DNA-binding high mobility group (HMG) domain, homologous to the HMG box of sex-determining region Y (SRY). Forming a subgroup of the HMG domain superfamily, SOX proteins have been implicated in cell fate decisions in a diverse range of developmental processes. SOX transcription factors have diverse tissue-specific expression patterns during early development and have been proposed to act as target-specific transcription factors and/or as chromatin structure regulatory elements. The protein encoded by this gene was identified as a SOX family member based on conserved domains and its expression in various tissues suggests a role in both differentiation and maintenance of several cell types. [provided by RefSeq
Other Designations
SOX-22 protein|SRY (sex determining region Y)-box 22|SRY-related HMG-box gene 22
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Interactome
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Publication Reference
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Sox12 promotes T reg differentiation in the periphery during colitis.
Tanaka S, Suto A, Iwamoto T, Kageyama T, Tamachi T, Takatori H, Suzuki K, Hirose K, Ohara O, Lefebvre V, Nakajima H.
The Journal of Experimental Medicine 2018 Oct; 215(10):2509.
Application：WB, WB-Tr, Mouse, CD4+ T cells.
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Sox12 promotes T reg differentiation in the periphery during colitis.
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