SOX10 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-SOX10 full-length
Host
Human
Theoretical MW (kDa)
49.9
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-SOX10 antibody (H00006663-B01) by Western Blots.
SDS-PAGE Gel
SOX10 transfected lysate.
Western Blot
Lane 1: SOX10 transfected lysate ( 49.9 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — SOX10
Entrez GeneID
6663GeneBank Accession#
NM_006941.3Protein Accession#
NP_008872.1Gene Name
SOX10
Gene Alias
DOM, MGC15649, WS2E, WS4
Gene Description
SRY (sex determining region Y)-box 10
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease. [provided by RefSeq
Other Designations
OTTHUMP00000028515|OTTHUMP00000195094|SRY-related HMG-box gene 10|dominant megacolon, mouse, human homolog of
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