SOAT1 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human SOAT1 partial ORF ( NP_003092.4, 249 a.a. - 321 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
PPASRFIIIFEQIRFVMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRNPTVRWG
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
33.77
Interspecies Antigen Sequence
Mouse (85); Rat (89)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — SOAT1
Entrez GeneID
6646GeneBank Accession#
NM_003101Protein Accession#
NP_003092.4Gene Name
SOAT1
Gene Alias
ACACT, ACAT, ACAT1, RP11-215I23.2, SOAT, STAT
Gene Description
sterol O-acyltransferase 1
Omim ID
102642Gene Ontology
HyperlinkGene Summary
Acyl-coenzyme A:cholesterol acyltransferase (ACACT; EC 2.3.1.26) is an intracellular protein located in the endoplasmic reticulum that forms cholesterol esters from cholesterol. Accumulation of cholesterol esters as cytoplasmic lipid droplets within macrophages and smooth muscle cells is a characteristic feature of the early stages of atherosclerotic plaques (Cadigan et al., 1988 [PubMed 3335499]).[supplied by OMIM
Other Designations
acyl-Coenzyme A: cholesterol acyltransferase|sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1
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Interactome
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Disease
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