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Last updated: 2017/11/19

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SOAT1 rabbit monoclonal antibody

  • Catalog # : H00006646-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human SOAT1 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human SOAT1 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human SOAT1 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • Application Image
  • Western Blot (Transfected lysate)
  • Gene Information
  • Entrez GeneID:
  • 6646
  • GeneBank Accession#:
  • SOAT1
  • Gene Name:
  • SOAT1
  • Gene Alias:
  • Gene Description:
  • sterol O-acyltransferase 1
  • Gene Summary:
  • Acyl-coenzyme A:cholesterol acyltransferase (ACACT; EC is an intracellular protein located in the endoplasmic reticulum that forms cholesterol esters from cholesterol. Accumulation of cholesterol esters as cytoplasmic lipid droplets within macrophages and smooth muscle cells is a characteristic feature of the early stages of atherosclerotic plaques (Cadigan et al., 1988 [PubMed 3335499]).[supplied by OMIM
  • Other Designations:
  • acyl-Coenzyme A: cholesterol acyltransferase,sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1
  • Gene Pathway
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