SMARCE1 (Human) IP-WB Antibody Pair
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More Files
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Immunoprecipitation of SMARCE1 transfected lysate using mouse monoclonal anti-SMARCE1 and Protein A Magnetic Bead (U0007), and immunoblotted with rabbit polyclonal anti-SMARCE1.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of SMARCE1 transfected lysate using mouse monoclonal anti-SMARCE1 and Protein A Magnetic Bead (U0007), and immunoblotted with rabbit polyclonal anti-SMARCE1.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: mouse monoclonal anti-SMARCE1 (300 ug)
2. Antibody pair for WB: rabbit polyclonal anti-SMARCE1 (50 ul)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — SMARCE1
Entrez GeneID
6605Gene Name
SMARCE1
Gene Alias
BAF57
Gene Description
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
Omim ID
603111Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart. [provided by RefSeq
Other Designations
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin e1|mammalian chromatin remodeling complex BRG1-associated factor 57
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Interactome
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Disease
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