SMARCE1 monoclonal antibody (M01), clone 6G11
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More Files
- More Functions
Immunoprecipitation
Immunoprecipitation of SMARCE1 transfected lysate using anti-SMARCE1 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with SMARCE1 MaxPab rabbit polyclonal antibody.
Western Blot detection against Immunogen (33.22 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant SMARCE1.
Immunogen
SMARCE1 (NP_003070, 75 a.a. ~ 142 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
RYSRKVWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQEYLNEYEAEKIEYNESMKAYHNSPAYLAY
Host
Mouse
Reactivity
Human
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (33.22 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Immunoprecipitation
Immunoprecipitation of SMARCE1 transfected lysate using anti-SMARCE1 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with SMARCE1 MaxPab rabbit polyclonal antibody.ELISA
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Gene Info — SMARCE1
Entrez GeneID
6605GeneBank Accession#
NM_003079Protein Accession#
NP_003070Gene Name
SMARCE1
Gene Alias
BAF57
Gene Description
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
Omim ID
603111Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart. [provided by RefSeq
Other Designations
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin e1|mammalian chromatin remodeling complex BRG1-associated factor 57
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Interactome
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Disease
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